What is obesity: Obesity is defined as body mass index (BMI) of 30 or above and current statics show that nearly 40% or over 93 million Americans meet this criteria. Obesity rates around the world continue to rise leading to higher rates of diabetes mellitus, high cholesterol, stroke, heart disease, cancer, metabolic syndrome, and multiple other conditions.
What causes obesity:
Causes of obesity involve various factors including hereditary predispositions, endocrine (that is, hormonal) abnormalities (for example, thyroid, cortisol, and pituitary abnormalities), poor dietary choices, levels of physical activity and sedentary lifestyle choices. In addition, psychological stress, mood disorders such as depression and anxiety can also lead to irregular and excessive food consumption and habits. The central nervous system has a central role in the pathophysiology of obesity. Central nervous system mechanisms for hunger, satiety, and food craving are now far better understood than even a decade ago. Using neuroimaging and neurophysiological studies, neuroscientists have identified several brain networks that are heavily involved in the control of cravings included that for food. In addition, a clear correlation exists between stress, anxiety, and many mood disorders and excessive food intake and obesity. Specifically, parts of the brain that control behavior and decision-making, often called ‘executive function’ have been mapped to the prefrontal cortex including the dorsolateral prefrontal cortex (DLPFC). This opens new possibilities in TMS therapy for weight loss.